We optimise the factory not the molecule
OptiGenomics redesigns CHO and HEK cell lines at the system level delivering performance gains that gene-by-gene approaches cannot reach.
Actively seeking new collaborations to extend our current portfolio of global CDMO and biopharma customers.
Our Approach
Incremental host engineering has reached its limits
Conventional approaches modify one variable at a time operating within a fraction of the available genetic space. The result is a ceiling in titre, in quality attributes and in manufacturability.
Our Platform
A Programmable Search Engine for Biology
We take a system-based approach to explore the breadth of genetic search space to find extreme performers. We search orders of magnitude beyond conventional methods.
And all this is tailored to your host cell line.
What we Do
Tailored host programmes for every modality.
Each engagement is configured to the specific requirements of the molecule and manufacturing context.
CHO Host Engineering
Purpose-built CHO production lines engineered for defined performance profiles. Titre, product quality, and process robustness addressed simultaneously at the host level including stable, accurate recombinant protein production.
HEK Host Engineering
Engineered HEK lines for complex modalities (including AAV and Lentiviral vectors). Host-level optimisation for applications where standard platforms fall short.
Genotype–Phenotype Mapping
Deep characterisation of the relationship between host genetics and production phenotype. With our system-based approach, we can diagnose your cells and find opportunities to boost performance.
Multi-Dimensional Optimisation
Simultaneous engineering across multiple genetic loci and performance dimensions. Coordinated interventions that single-variable methods cannot access.
Engagement
Partnership, not procurement
OptiGenomics operates as a development partner. We work within your programme objectives, timelines, and IP frameworks, from first experiment to technology transfer.
Pilot
Define objectives and success criteria on your cell line. Low-risk entry with clear deliverables.
Search & Embed
Multi-dimensional discovery and performance gains embedded directly into the host.
Transfer
Improved line delivered for your internal development. No ongoing dependency.
Manufacturing Integration
Designed to slot into existing manufacturing workflows without friction.
Working with Us
What Sets Our Partnership Model Apart
Programmes Scoped to your Host Cell Line
Configured to specific product and manufacturing requirements.
Clear Milestones and Decision Gates
Defined workflows from pilot to transfer.
Full Host Cell Line Ownership
Complete assignment to the partner on all engineered host lines.
Regulatory-ready Data Packages
Fully compliant data package for a successful regulatory submission.
Confidential by Design
Bilateral engagement from first contact.
About us
Who we are
OptiGenomics is a biotech company founded in 2024 in Oxford, UK. We bring together deep expertise in cell biology, genetics, AI, and bioprocess engineering focused on one problem: unlocking host performance at scale.
Leadership & governance
A team built for execution, scientific rigour, and long-term partnership with R&D organisations.
Dr Harsh Amin
Chief Executive Officer
Dr Iain Alasdair Russell
Chairman of the Board
Mr Konstantin Solodovnikov
Board Member
Dr Stefan Schmidt
Advisor
Ready to boost your host cell line performance for your manufacturing needs?
Whether you are evaluating a new cell line strategy or exploring long-term platform partnerships, we are open for discussion.
